Clustering clinical trials with similar eligibility criteria features
نویسندگان
چکیده
منابع مشابه
Analysis of Eligibility Criteria Complexity in Clinical Trials
Formal, computer-interpretable representations of eligibility criteria would allow computers to better support key clinical research and care use cases such as eligibility determination. To inform the development of such formal representations for eligibility criteria, we conducted this study to characterize and quantify the complexity present in 1000 eligibility criteria randomly selected from...
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Use of major eligibility criteria is a popular but unstudied folk practice for improving patient screening efficiency for clinical studies. This mixed-methods research study derived the desiderata for major eligibility criteria in breast cancer clinical trials. We randomly selected thirty interventional breast cancer clinical trials conducted at The New York-Presbyterian Hospital on the Columbi...
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Towards the goal of automated eligibility determination for clinical trials from electronic health records, we propose a method to formulate Semantic Web based queries using the free-text eligibility criteria on clinicaltrials.gov.
متن کاملDynamic categorization of clinical research eligibility criteria by hierarchical clustering
OBJECTIVE To semi-automatically induce semantic categories of eligibility criteria from text and to automatically classify eligibility criteria based on their semantic similarity. DESIGN The UMLS semantic types and a set of previously developed semantic preference rules were utilized to create an unambiguous semantic feature representation to induce eligibility criteria categories through hie...
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In this paper, we propose a rule-based formalization of eligibility criteria for clinical trials. The rule-based formalization is implemented by using the logic programming language Prolog. Compared with existing formalizations such as pattern-based and scriptbased languages, the rule-based formalization has the advantages of being declarative, expressive, reusable and easy to maintain. Our rul...
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ژورنال
عنوان ژورنال: Journal of Biomedical Informatics
سال: 2014
ISSN: 1532-0464
DOI: 10.1016/j.jbi.2014.01.009